but overlapping pathogenic mechanisms leading to either excessive acid secretion or diminished mucosal defense. They are common entities present in daily clinical practice that, owing to their ...

Many experts maintain that GERD is caused by dysfunction of the gastroesophageal barrier and that gastric acid secretion is not the primary underlying defect. 2 A few studies have, however, raised ...

Reimer and colleagues recognized that rebound acid secretion had been documented ... Gastroenterology 137, 20–22 [2009]). The mechanisms of rebound acid hypersecretion are well-recognized ...