Purpose: The efficacy and tolerability of quetiapine in the treatment of acute mania were reviewed. Summary: Five randomized, placebo-controlled trials involving quetiapine as monotherapy or ...

This study demonstrated the efficacy of quetiapine as monotherapy for acute mania ... As the goal in the treatment of mania is to achieve remission, these missing data limit the interpretability ...

Interestingly, the first English language report on the use of antipsychotic agents in schizophrenia also showed that these drugs have efficacy in the treatment of acute mania, which clinicians ...

The protein kinase C (PKC) signaling cascade has been identified as a direct biochemical target for the treatment of mania. Preclinical studies and early clinical trials have shown that the ...

Treatment varies from person to person because ... A doctor may prescribe an antipsychotic medication if you’re experiencing acute manic episodes that require hospitalization.

Manic episodes in bipolar I disorder require treatment with drugs ... It is faster-acting than lithium for an acute episode of mania. It is also often used "off-label" for the prevention ...