CD8-positive T cells are a critical subpopulation ... Calcium signalling is an essential feature of T cell activation. Here authors employ CaCO 3 nanoparticles to facilitate the expansion and ...

Their study, published in Oncogene, explores how increased methylmalonic acid impairs the activation and effector functions of CD8+ T cells, immune cells that play a vital role in fighting cancer.

Findings indicate a serine/glycine-free diet can reduce colorectal cancer growth and enhance immune response, offering ...

Cancer cell death via necroptosis can be accompanied by the release of IL-1a, which can restrict anticancer immunity and ...

MDNA11 is a next-generation IL-2 superkine designed to selectively stimulate effector immune cells (CD8 + T cells and NK cells) by enhancing affinity for IL-2Rβ (CD122) while avoiding IL-2Rα (CD25), ...

Memory CD8 + T cells are the mature version that has encountered an antigen before and create an immune response if it is reencountered. Lower levels of apoptosis were also seen in the CD4 + T cells ...