The selective advantage for the establishment and, more interestingly, the maintenance of heterogeneity in tumors is unclear. Our results indicate that tumors benefit collectively from protecting ...

However, it is becoming increasingly apparent that the huge diversity of microbial pathogens prompts the development of a wide array of appropriate T cell responses. Consequently, an emerging ...

Access to single cell resolution reveals new insights into how the human body and its cells operate during health and disease. Cellular heterogeneity is a vital part of physiological function, and the ...

A. Wiens 3. Generation of heterogeneity by organisms: creation, maintenance and transformation S. T. A. Pickett, M. L. Cadenasso and C. G. Jones 4. Heterogeneity, diversity and scale in plant ...

Research shows that GBM organoids are a powerful, accurate tool for understanding what happens when treating a brain tumor ...

The scAtlasVAE model integrates scRNA-seq data to create a CD8+ T cell atlas, enhancing understanding of immune responses in ...

Modern day drug discovery is shifting from single end point assays to more complex phenotypic assays that query single cell ...

Single-cell proteomics plays a crucial role in explaining ... including studies on cellular heterogeneity, spatial proteomics ...