Reactive oxygen production and the ensuing cellular response can be strongly influenced by lifestyle factors such as the intensity and frequency of exercise. Traditionally, ROS are viewed as imposing ...

Unregulated ROS release can damage mitochondria ... "This studies further highlights how metabolism of immune cells is a target for potential novel therapies and we are working in this space ...

In contrast, the genetic determinants of glutamine uptake and metabolism during cell growth have not been determined ... As predicted by our collaborator, Celeste Simon, this HIF-dependent regulation ...

Ferroptosis represents a distinct cell death pathway regulated by iron metabolism, ROS production, and lipid peroxidation. The primary trigger for ferroptosis involves excessive accumulation of ...