Cerebral spinal fluid examination revealed ... No neurofibrillary tangles or amyloid plaques were found in the parenchyma. Reactive gliosis, strong upregulation of microglia and multiple ...

Brain scans reveal different patterns of white matter injury, highlighted in various colors, that result from cerebral small ...

Cerebral amyloid angiopathy (CAA) is a common but often asymptomatic disease, characterized by deposition of amyloid in cerebral blood vessels. We describe the successful treatment of CAA ...

Researchers at Washington University School of Medicine in St. Louis have been awarded $7.5 million from the National Institutes of Health (NIH) to investigate a form of dementia caused by cerebral ...

Figure 1. Aged cynomolgus monkey. Cerebral amyloid angiopathy involves blood vessels of the meninge (A), frontal cortex (FC), parietal cortex (Par C), and amygdala (Amyg) with additional β ...

Mivelsiran is in Phase 1 in AD, and in Phase 2 for cerebral amyloid angiopathy. Previously, Mummery had presented interim safety and biomarker data from a single-ascending-dose trial in people with ...

Investigations. Physical examination, laboratory tests, brain CT scan, brain MRI scan, brain magnetic resonance angiogram, brain magnetic resonance venogram, cerebral angiography, transcranial ...

which is developing ALN-APP in collaboration with Regeneron for both Alzheimer’s and related condition cerebral amyloid angiopathy (CAA), which can cause haemorrhaging in the brain. Eisai and ...

Most of my current research is in Alzheimer's disease and concerns the metabolism and clearance of soluble, insoluble and oligomeric forms of Abeta, alterations in Abeta-degrading enzymes, impairment ...