The processes that mediate target recognition and signal transduction in biosensors ... triggered self-assembly of DNA nanostructures in a novel process they term hybridization chain reaction ...

The CHA mechanism enhances the specificity and sensitivity of nucleic acid detection by facilitating the hybridization of DNA ...

(A) FISH produces a fluorescent signal (red) at the sites of a specific DNA sequence; in this case, a 150-kb segment of chromosome 1. (B) Several probes, each corresponding to a defined genomic ...