Allogeneic dendritic cells provide both ‘stranger’ and ‘danger’ signals to the immune system that are crucial for it to sense a cell-associated threat such as cancer. These signals ...

As dendritic cells increasingly become the adjuvant of choice in new approaches to cancer immunotherapy, a degree of protocol standardization is required to aid future large-scale clinical trials.

Dendritic cells are poised to revolutionize oncology. This type of immune therapy shows effectiveness even in late-stage ...

In recent decades, immunotherapy has transformed cancer treatment, offering effective options for diseases once considered ...

Medical researchers have developed vaccines that train immune cells to fight cancer, but delivering these vaccines to the right cells remains a critical challenge. The vaccines must reach specialized ...

we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse types of cancer and can ...

Various cell types contribute to dysregulation of immune responses in MDS. Dendritic cells (DCs) are important regulators of immunity. However, the role of DCs in MDS has yet to be elucidated.

One prostate cancer vaccine, Provenge, was shown to lengthen the life of men with widespread disease. It also is a dendritic vaccine -- dendritic cells are taken from a man, "taught" to recognize ...

They help the immune system recognize cancer cells that impersonate healthy cells. However, the effectiveness of these ...

It induces a specific type of immunity, called Th17 immunity, that seems to prevent suppression of the immune system. The ...

Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize ...