Rather, it is an active process of destruction, as confirmed by the discovery of the Wallerian degeneration slow (Wld s) mouse. In this spontaneous mutant, the breakdown of the distal stump axon ...

previously shown to cause neurotoxicity and axonal degeneration, using a rodent dorsal root ganglia model of distal symmetric polyneuropathy. They found that gp120 causes neuronal apoptosis and ...

Axon degeneration. Neurotmesis V Complete loss of neural continuity. M1 Return of contraction in the proximal muscles M2 Return of contraction in both proximal and distal muscles M3 Return of ...

This disruption leads to axonal dystrophy and degeneration, ultimately resulting in severe neurological impairments." To carry out their experiments, Bonifacino and his collaborators leveraged the ...