Epigenetics involves genetic control by factors ... After they are incorporated into DNA, the drugs block DNMT enzymes from acting, which inhibits DNA methylation. Drugs aimed at histone ...

She said it might one day be possible to target epigenetic enzymes that install or remove methyl groups on CpGs. "Those ...

Many promising agents have been identified that behave as inhibitors of key enzymes involved in establishing and maintaining the epigenetic profiles of specific cell types through the process of ...

One common marker is DNA methylation, which occurs when the enzyme DNA methyltransferase adds a methyl group to the DNA base cytosine. Although the cytosine remains cytosine, the methyl add-ons make ...

One common marker is DNA methylation, which occurs when the enzyme DNA methyltransferase adds a methyl group to the DNA base cytosine. Although the cytosine remains cytosine, the methyl add-ons make ...

In the opening lecture, Stephen Baylin, [2] of Johns Hopkins University, Baltimore, Maryland, provided an overview of the basic mechanisms underlying epigenetic gene silencing. Genes can be ...