These include acetylation, methylation, ubiquitinylation, phosphorylation, poly-ADP ribosylation, sumoylation, carbonylation and glycosylation, although many of these modifications have not been ...
In this webinar, we will focus on the relevance of modifications, particularly DNA methylation at the fifth position of cytosine (5mC), in studying disease mechanisms in humans. We will present ...
Methylation of CpG islands is generally associated with gene silencing ... This plasticity of epigenetic marks highlights the importance of understanding how lifestyle and environmental factors can ...
The epigenome comprises a tissue-specific profile of DNA methylation, histone modifications, nucleosome remodeling and RNA-associated silencing (Figure 1), which collectively result in heritable ...
Because the brain is made from many types of cells, analysis of DNA methylation status of neurons is difficult. In this study, we will develop advanced technologies to analyze epigenome in neurons and ...
Methylation is an example of epigenetics that ... This collaboration aims to capture the full spectrum of the epigenome, or epigenetic markers across the genome, in a fast-evolving area of ...