Evox is engineering exosomes—lipid-membrane-containing nanoparticles constitutively produced by cells—and loading them with protein therapeutics or nucleic-acid-based agents (Fig. 1).

The saccharide acts on exosome production by elevating levels of Ras-related protein 7 (Rab7). Trehalose SG also improves purification yields. Adding the saccharide suppresses exosome aggregation ...