A modular genetic switch that tightly regulates gene expression in mammalian cells will be useful in the design of complex synthetic gene circuits. One of the goals of synthetic biology is the ...

Using silencer-seq, the Stark lab identified 800+ silencers and the transcription factor Saft in fruit flies, enhancing our ...

Yen and his colleagues developed a system that turns genes on to different levels on cue using small molecules at FDA-approved doses. The switch is placed in the RNA, the copy of genetic material ...

What makes the cells differ from one another is that different genes in that DNA are either turned on or off in each type of cell. Take a typical cell, such as a red blood cell. Each gene within ...

This was the same gene. We thought of this gene as a sort of master switch. You can compare this to an electrical switch: When you come into a house, you can switch on the current with the main ...

Gene editing is a relatively recent technology. It involves switching genes on and off by snipping out a small section of the plant's DNA. The older technique of genetic modification involves ...

Some sequences in the genome cause genes to be switched on or off. Until now, each of these gene switches, or so-called ...

Exercise can switch on FOXO3 by alerting it “that it ... of antioxidants that reduces inflammation. How quickly the gene is ...

The human 'master switch' for sex In mammals, females have two X chromosomes, whereas males have an X and a Y. The Y chromosome bears a gene called SRY, which acts as a "master switch": an XY ...