How do scientists develop new treatments for disease? With Gleevec, a remarkable cancer drug, the approach was to target the disease at the cellular and subcellular level. When people say Gleevec ...

What distinguishes imatinib from chemotherapy is that we know which patients will benefit from this drug and why. This was made possible by numerous scientific discoveries that allowed a precise ...

And this was a definite unmet medical need, because chemotherapy never worked. GEORGE DEMETRI: As much as Gleevec was lifesaving and breakthrough and, and a revolution for the people with GIST ...

Brian Druker, MD, whose discovery of imatinib (Gleevec) paved the way for targeted cancer therapies, announced his ...

to imatinib – sold by Novartis as Glivec/Gleevec, but also available as a generic – on top of a reduced-intensity chemotherapy regimen in 230 patients with this type of leukaemia. According to ...

Chemo didn’t just poison cancer cells ... Novartis produced a compound known as imatinib that worked in the test tube. It worked in mice. It worked in rats. But would it work in humans?

Medically reviewed by Gagandeep Brar, MDChemotherapy often causes hair loss, but it can depend on the type of chemo drug as ...

Romine became the first CML patient ever to be treated with the new compound, now called Gleevec. Traditional chemotherapy works by blasting away at all fast-growing cells, which includes cancer ...

The drug is effective as a first-line treatment, especially in older patients, when combined with chemotherapy. Imatinib targets the BCR-ABL anomaly, achieving complete hematologic response in ...

In 2001, a Time Magazine cover story touted Novartis’ targeted leukemia treatment Gleevec (imatinib) as a new kind of “ammunition in the war against cancer.” Along with a picture of the ...