Antipsychotics commonly used in the treatment of schizophrenia target dopamine receptors, but there is growing evidence that altered glutamate transmission is important in the pathophysiology of ...

Glutamate had already been identified as potentially implicated in the development of schizophrenia (also in other neurodegenerative diseases, such as Alzheimer's), but there is now solid genetic ...

Mayo Clinic says that problems with certain naturally occurring brain chemicals, including neurotransmitters called dopamine ...

The drug is a sodium channel blocker thought to work by blocking the post-synaptic release of glutamate, a neurotransmitter, and offering an alternative mechanism to existing schizophrenia drugs ...