This fundamental biologic process is defined by a series of complex metabolic processes, which are often dysregulated in blood disorders such as sickle cell disease and β-thalassemia. St. Jude ...

In particular, the work reveals that modulating glutamine metabolism is a potential therapeutic route for common red blood cell disorders. Additionally, glutamine abundance may serve as a tool for ...

identified and characterized a previously unrecognized fundamental role for glutamine in blood cell development.

“We were surprised to discover that KMT could work synergistically with the IDH1 mutation to simultaneously target the two major metabolic pathways needed to drive the growth of GBM,” said Seyfried.

Tumor cells often display fundamental changes in metabolism and increase their uptake of nutrients to meet the increased bioenergetic demands of proliferation. Glucose and glutamine are two main ...

This study investigated the effect of L-glutamine supplementation on DOMS after 30 min ergometric exercise by comparing two metabolic enzymes (aldolase and creatine kinase) and hip flexors range of ...