Innate immunity is the oldest and most conserved facet of the immune system. It is responsible for an anti-infective response and it has been intrinsically linked to the initiating of inflammation.

Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non–Toll-like innate immune proteins. One of the more important revolutions in immunology ...

These therapies employ a different branch of the immune system called innate immunity that can help overcome cancer’s ability to evade immune recognition early in an immune response. By ...

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways—ways that have important implications for the development ...

Trained immunity responders produced fewer mediators before vaccination and started with more dormant innate immune cells ...

Our recent study links autophagy to innate immunity toll-like receptor 4 (TLR4). Further, it defines the signaling pathway downstream from TLR4 via TRIF/RIP1/p38MAPK. This pathway maintains cell ...

2024年11月22日，中国科学院微生物研究所刘宏伟研究团队在Advanced Science上发表了题为“Postbiotics From Lactobacillus Johnsonii Activates Gut Innate Immunity to Mitigate Alcohol-Associated Liver Disease”的研究论文，研究发现灭活后的约氏乳杆菌（ ...

The vaginal innate immune system represents the first line of defense against foreign organisms and pathogenic microbes. Through its major components, a natural balance is maintained and disease ...

We are testing the hypothesis that stress granules are staging platforms that activate or amplify downstream innate immune signaling. This could be a major function of stress granules that all viruses ...

How chronic activation of the innate immune system can lead to cancer The newer paper, led by first author Hexiao Wang, Ph.D., a postdoctoral fellow in the Petrini Lab, and published in Genes ...

MSK researchers discovered that the innate immune system's chronic activation due to issues in the Mre11 complex can lead to ...

With seasonal changes, immunity often weakens, making it essential to adopt natural ways to strengthen it. One such superfood ...