随着结核分枝杆菌感染的全球流行,准确的检测方法变得尤为重要。γ-干扰素释放试验(interferon-γreleaseassay,IGRA)是现代医学中用于检测结核分枝杆菌感染的主要工具之一,因其高特异性且不受卡介苗(BCG)接种影响,已在全球范围内广泛应用。 目前,常用的IGRA方法包括Quantiferon-TBGold(QFT)和T-SPOT.TB。本文将重点讨论QFT的检测原理、结果类型以 ...
For example, activated T helper type 1 lymphocytes secrete interferon (IFN)-γ, which has potent effects on osteoclastogenesis in vivo and in vitro. IFN-γ, however, is known to cause both bone ...
The function of human airway macrophages can be therapeutically manipulated by targeting cellular metabolism to support immunity in the lung, aiding the design of innovative strategies in respiratory ...