Disruptions in the delicate balance between keratinocyte proliferation and differentiation can contribute towards the development of squamous cell carcinoma (SCC) of the skin — a common human ...

Next, Monteleone et al. investigated whether IL-21 can induce keratinocyte proliferation and epidermal hyperplasia as seen in psoriasis. Keratinocytes from healthy volunteers were shown to ...

Understanding the mechanisms that drive the transition from an inflammatory to a proliferative phase during wound healing can aid in developing novel strategies for enhanced tissue repair.

The end of the inflammation phase is characterized by the presence of peptides needed during the subsequent phase, proliferation ... using the human keratinocyte-derived cell line HaCaT, the ...