The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous with one another. Therefore, the membrane lipids and proteins that are synthesized in ...
He labeled proteins and followed them in their journey ... they established that after autophagosomes form, they fuse to the lysosomal membrane to form a structure known as the autolysosome ...
The gut of animals is a complex ecosystem consisting of trillions of bacteria and other microorganisms that are unique to every individual. Infants can inherit their first gut bacteria through vaginal ...
They were able to identify a previously unknown signaling pathway in human cells that is driven by the protein SPG20. It recognizes damage to the outer side of the lysosomal membrane, binds to the ...
Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...