Initially 12g/m 2 IV infusion over 4 hours; may be increased to 15g/m 2; see literature for leucovorin rescue dosing with high-dose methotrexate. Be fully familiar with this drug's toxicity before ...

In rheumatoid arthritis, methotrexate helps decrease the activity of the immune system. This article explains drug and food ...

We also discuss potential strategies to deal with drug resistance. Slow transport via folate receptor (lower affinity for methotrexate than for folic acid) Increased drug efflux via ATP-binding ...

Methotrexate is prescribed for psoriasis and certain cancers. It's a generic medication, available as the brand-name drugs Trexall, Xatmep, and more. It comes as an injectable IV solution ...

Nat Clin Pract Rheumatol. 2007;3(1):26-34. Slow transport via folate receptor (lower affinity for methotrexate than for folic acid) Increased drug efflux via ATP-binding cassette (ABC) subfamily ...

The drugs are listed in alphabetical order. Adalimumab-Adbm injection: Boehringer Ingelheim Pharmaceuticals discontinued two presentations of Cyltezo, its biosimilar to Humira. The injectable ...

Leucovorin Calcium Injection contains calcium folinate. It belongs to a group of vitamins used as an antidote to the harmful effects of methotrexate therapy. Calcium folinate acts in the same way ...