N-methyl D-aspartate (NMDA) receptors are ligand-gated cation channels activated by glutamate, an excitatory neurotransmitter. These receptors are located mostly at excitatory synapses and ...

Metabotropic glutamate receptors exist as both homo- and heterodimers. Here, the authors report the mGlu2-4 receptor structures in the inactive, intermediate and active states, and reveal the ...