Individuals with DS develop age-dependent cognitive decline and ... synaptic function, and neuroinflammation in a mouse model ...

French researchers have revealed a selective GABA inverse agonist has restored cognitive function in a mouse model of Down's syndrome (DS ... showed a clear learning impairment that was reversed ...

This research explores the interaction between microglial dysfunction and mitochondrial impairment ... to reduce neuroinflammation and neuronal loss, thereby improving cognitive function in ...

Recent advances in neurobiology and PET have helped redefine Alzheimer's disease (AD) as a dynamic pathophysiological process, clinically characterized by preclinical, mild cognitive impairment ...