Marini et al., therefore, conducted a 2-year randomized trial of genistein versus placebo in 389 osteopenic postmenopausal women. The authors conclude that genistein improves BMD and bone-turnover ...
In this study, alendronate reduced vertebral fracture rates among osteopenic postmenopausal women. However, the absolute benefit was very small among women without vertebral fractures at baseline.