胃肠间质瘤（gastrointestinal stromal tumor，GIST）是胃肠道常见的间叶源性肿瘤，在生物学行为上可从良性至恶性，免疫组化检测通常表达CD117和DOG1阳性，显示卡哈尔细胞（Cajal ...

While many GISTs share common mutations in KIT or PDGFRA, their clinical behavior varies significantly. This study sheds ...

Blueprint Medicines’ total revenues comprise net product revenues from Ayvakit/Ayvakyt and collaboration revenues. Ayvakit (avapritinib), an inhibitor of KIT and PDGFRA proteins, is approved for ...