Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...
Mutations in a complex that helps proteins fold correctly are tied to developmental disorders that include seizures and intellectual disability, Stanford Medicine-led research has found.
Cicmil is particularly interested in proteins with hydrophobic pockets—potential binding sites for new drugs—that undergo the process of autopalmitoylation, which determines where the protein goes and ...
New research has detailed how UNC45, a protein chaperone, distinguishes between healthy and faulty myosin in muscle cells, guiding them to either proper assembly or degradation. Chaperones are ...