ACE inhibitors are commonly used to treat hypertension and they act by decreasing levels of angiotensin II, a potent vasoconstrictor. Drugs in this class also decrease ACE-dependent degradation of ...
Newer drugs act on the renin–angiotensin system ... while ACE further converts it to angiotensin II — a potent vasoconstrictor among other things — leading to an increase in blood pressure.
The IN route potentially improves systemic bioavailability of drugs since it bypasses gastrointestinal ... decongestant (pseudoephedrine) or nasal vasoconstrictor (oxymetazoline) on the rate ...