Screening VHH pairs creates an unbiased pool of antibodies with broader functionality, and through selection of optimal linkers even low-affinity, single-epitope binders function synergistically ...

Originally derived from camelid heavy chain antibodies, single domain or VHH antibodies can bind epitopes that are inaccessible to conventional monoclonal antibodies due to their small size. Because ...

a trispecific antibody designed as a prophylaxis and therapeutic against SARS-CoV-2 infection. Using in-house phage libraries of naïve and synthetic humanized llama nanobodies (VHH), the Ab ...

This work presents a valuable exploration of AI-assisted protein engineering, particularly in designing a VHH antibody with enhanced resistance and stability to extreme environments. However, the ...

The separated edges of these antibodies are known as VHH antibodies, or nanobodies, which are smaller, easier to modify and more stable. The team has been working on an antibody that can work ...

The antibody is a protein that can bind to viruses. The team selected and researched one known as the VHH antibody. That antibody comes from a camelid, a group of mammals that includes camels and ...

Single domain antibodies (sdAbs), also known as VHH antibodies or nanobodies™, are small antigen-binding fragments derived from camelids that have a single monomeric variable antibody domain. sdAbs ...

Scinai Immunotherapeutics (NASDAQ: SCNI) has appointed Dr. Jonathan Sadeh to its Scientific Advisory Board, where he will support the advancement of the company’s IL-17 program and VHH antibody ...

Bright Biologics LLC reported the discovery and preclinical evaluation of BB-203, an anti-PD-L1/anti-VEGF bispecific antibody (Ab) being developed for the treatment of cancer.