Cetirizine is an over-the-counter (OTC) antihistamine. Pseudoephedrine is a decongestant. Zyrtec-D is an OTC combination medication of the two. Decongestants help relieve nasal congestion by ...

When treating mild allergic reactions, allergists and pediatricians prefer children’s Zyrtec over children’s Benadryl. OTC allergy medications cannot treat extreme allergic reactions ...