The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Normal red blood cells are round and pliable. With sickle cell ...

Sickle cell disease (SCD) is a pressing global health issue, with rising cases and mortality, especially in low- and middle-income countries (LMICs). Hydroxyurea, a cost-effective treatment for ...

A breakthrough at the Lagos University Teaching Hospital, Idi-Araba, has brought cheery news to people with sickle cell disease. LUTH doctors working with an NGO, Sickle Cell Foundation of Nigeria ...

As he got older, he learned he had sickle cell disease: His red blood cells were forming sickle shapes and getting stuck in his blood stream, preventing oxygen from reaching his tissues.

there are an estimated 11,000 individuals living with Sickle Cell Disease in California. The Networking California for Sickle Cell Care network serves 960 adults across 12 clinical sites and two ...

SAN DIEGO — Pfizer’s abrupt withdrawal of its sickle cell drug Oxybryta over safety concerns was called “tone deaf” during a panel discussion among sickle cell experts Saturday at STAT@ASH ...

(BEAM) announced new safety and efficacy data from its BEACON Phase 1/2 clinical trial of BEAM-101 in patients with sickle cell disease (SCD) with severe vaso-occlusive crises (VOCs). Updated data ...

In Morbidity and Mortality Weekly Report, three new studies describe increased infections of parvovirus B19 detected in US commercial labs, with five worrisome cases in pregnant Minnesotans and ...

SAN DIEGO — The approval one year ago of two genetic medicines for sickle cell disease, including the first therapy powered by CRISPR gene editing, was a milestone for people living with a ...

Called Casgevy, the gene-editing treatment is for people with sickle cell disease and a related blood disorder called beta thalassemia. UK regulators approved the treatment in November 2023 ...

Dec. 5, 2024 — Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a ...

Cell signaling is crucial for cells to communicate ... leading to dysfunction and disease. 12 Cells generate reactive oxygen species (ROS) as byproducts of metabolism. 12 Dysregulation of ...