Functional protein design, particularly for proteins ... complex molecular–protein interactions and capturing sequence-structure dependencies. PocketGen addresses these issues, offering a ...
Once a protein has its shape, it can bind to other selected molecules in order to carry out its function. That function could be signaling, storing, transporting, providing structure, fighting foreign ...
A protein has many identities and one of them depends on the arrangement of its amino acids in the three dimensions of space — in other words, its 3D structure. And scientists have spent decades ...
This issue is especially significant in designing functional proteins, including enzymes and molecular binders ... Moreover, these approaches struggle with achieving the trade-off between ...
As an essential component of the human body, collagen is often hailed as the most abundant protein in our system. This fibrous, yet flexible, molecule plays a pivotal role in supporting the structure ...