This work will be of high interest to a broad swathe of scientists studying native macromolecules present at low concentrations in cells. Cryo-EM single-particle analyses typically require target ...

A cryo-EM structure of the full-length DNMT3A1-DNMT3L complex with a H2AK119ub nucleosome reveals that the DNMT3A1 ubiquitin-dependent recruitment (UDR) motif interacts specifically with H2AK119ub and ...

“Fashion continues to turn against hatches so the 1 Series range has shrunk. But if a petrol auto suits you, this is a fine car” It's one of the most satisfying compact hatches aroun ...

State Key Laboratory of Natural Medicines, Department of Organic Chemistry, China Pharmaceutical University, Nanjing 210009, China ...

JN.1 has been found in many countries around the world, including India, China, UK and the United States. The risk to the public is currently low and current vaccines continue to offer protection ...

We report cellular, genetic, biochemical, substrate selectivity, and crystallographic studies providing evidence that an additional endoribonuclease, MBL domain containing protein 1 (MBLAC1), is ...