More from Developmental Cell - Cell Press
Developmental Cell publishes peer-reviewed articles within and at the interface of cell biology and developmental biology.
Information for authors: Developmental Cell - Cell Press
Developmental Cell launched in 2001 as a journal intended to bridge the disciplines of cell biology and developmental biology. The scope of the journal now encompasses not only both cell biology and developmental biology but also all of the diverse fields …
Editors and staff: Developmental Cell - Cell Press
This journal is part of Cell Press Multi-Journal Submission; click here to learn about their Editorial team. This journal is supported by our Cell Press team of Cross-Journal Editors.
From nuclear to extracellular PTEN: Multiple roles in ... - Cell Press
2024年12月2日 · The work published in Developmental Cell introduces a new dimension to PTEN function and demonstrates that PTEN can be secreted into extracellular matrix via the TMED10-channeled pathway. Loss of the secreted PTEN impairs its ability to regulate macrophage differentiation, and thereby promotes tumor immune evasion ( Figure 1 ).
A novel Ca2+ sensor switch for elevated salt tolerance in plants
2022年9月12日 · In this issue of Developmental Cell, Steinhorst et al. show that salt stress quantitatively translates into an increasing Ca 2+ signaling output that activates the CBL8-CIPK24-SOS1 module, which, functioning with CBL4-CIPK24-SOS1, confers enhanced salt tolerance under severe salinity stress.
Comparative single-cell analyses identify shared and ... - Cell Press
2024年8月8日 · Kim et al. employed in-depth single-cell/-nuclear transcriptomics and open chromatin accessibility analyses to developing human and mouse kidneys. Cross-species, multiomic integration identified conserved and human-enriched features of developmental, functional, and evolutionary kidney programs.
A subset of neutrophils activates anti-tumor immunity and ... - Cell …
2024年11月7日 · Deleting CD74 in IL-8-humanized neutrophils impairs T cell activation and exacerbates NSCLC progression, whereas a CD74 agonist enhances T cell activation and the efficacy of anti-programmed cell death 1 (PD-1) or osimertinib therapies.
Issue: Developmental Cell
2024年10月7日 · In this review, La Marca et al. delve into the role of cell death in tumorigenesis; particularly apoptosis, but also touching on emerging roles for other cell death variants. The review also discusses the development, limitations, and future of BH3-mimetics, the most clinically advanced class of compounds for direct apoptosis induction.
A Single-Cell Transcriptomic Atlas of Human Skin Aging - Cell Press
In this study, we provide a broad survey of the single-cell transcriptional landscapes by which to systematically annotate human skin cell types and to fine-map discrete sets of cell-type-specific aging-regulated genes and core TFs that help elucidate the complex biology of human skin aging.
Issue: Developmental Cell
2024年8月5日 · Zhang et al. demonstrate that the E3 ubiquitin ligase OsRING113, a positive regulator of broad-spectrum disease resistance, ubiquitinates and targets the negative regulator of programmed cell death APIP5 for degradation.