Bases follow-up testing on the difference between bilirubin level and the phototherapy threshold. No more risk zones! Raises thresholds for phototherapy and exchange transfusion. Includes gestational age and risk factors for neurotoxicity in the thresholds. Adds when to check for rebound after stopping phototherapy.
For the baby 1.4 mg/dL below the phototherapy threshold (Δ-TSB) at 48 hours of age (during birth hospitalization with no prior phototherapy): Measure TSB in 4 to 24 hours. Options: (1) Delay discharge and consider phototherapy. (2) Discharge with home phototherapy if all considerations in the guideline are met.
This is why GA is required to identify the phototherapy and exchange transfusion thresholds. It is included here for completeness. * You can toggle this list in the dropdown menu to the left:
The last age/bilirubin dataset evaluates the treatment thresholds, escalation of care, reflex testing, postdischarge recommendations, etc. The last two paired age/bilirubin datasets are used to establish the rate of change .
TcB measures have been shown to have good correlation with TSB concentrations, generally falling within 3 mg/dL for TSB concentrations <15 mg/dL. The AAP recommends a TSB if the TcB exceeds or is within 3 mg/dL of the phototherapy treatment threshold or if the TcB is ≥15 mg/dL.
From Key Action Statement (KAS) 6, the AAP recommends that bilirubin should be confirmed with serum bilirubin if a transcutaneous bilirubin (TcB) "exceeds or is within 3 mg/dL of the phototherapy treatment threshold or if the TcB is greater than or equal to 15 mg/dL".
For the baby 3.2 mg/dL below the phototherapy threshold (Δ-TSB) at 24 hours of age (during birth hospitalization with no prior phototherapy): Check TSB or TcB in 4 to 24 hours. Use clinical judgment and shared decision making to determine when to repeat the bilirubin measure within this 4 to 24 hour period.
The last age/bilirubin dataset evaluates the treatment thresholds, escalation of care, reflex testing, postdischarge recommendations, etc. The last two paired age/bilirubin datasets are used to establish the rate of change .
Predischarge TSB or TcB close to phototherapy threshold. Hemolysis from any cause if rapid rate of increase of bilirubin >0.3 mg/dL/hour in first 24h or >0.2 mg/dL/hour thereafter. Phototherapy before discharge. Parent/sibling requiring phototherapy or exchange transfusion. Exclusive breastfeeding with suboptimal intake. Scalp hematoma or ...
Predischarge TSB or TcB close to phototherapy threshold. Hemolysis from any cause if rapid rate of increase of bilirubin >0.3 mg/dL/hour in first 24h or >0.2 mg/dL/hour thereafter. Phototherapy before discharge. Parent/sibling requiring phototherapy or exchange transfusion. Exclusive breastfeeding with suboptimal intake. Scalp hematoma or ...