SHIFT: speedy histological-to-immunofluorescent translation of a tumor ...
2020年10月15日 · In this work, we present a deep learning-based method called speedy histological-to-immunofluorescent translation (SHIFT) which takes histologic images of hematoxylin and eosin (H&E)-stained...
Images of immunohistochemical staining of ZNF365 and P
Download scientific diagram | Images of immunohistochemical staining of ZNF365 and P-p53 (Ser15) in CRC tissues. ZNF365 protein expression was positively correlated with P-p53 (Ser15) expression ...
Computational Staining of Pathology Images to Study the Tumor ...
2020年5月15日 · To facilitate the study of cellular spatial organization and interactions, we developed Histology-based Digital-Staining, a deep learning-based computation model, to segment the nuclei of tumor, stroma, lymphocyte, macrophage, karyorrhexis, and red blood cells from standard hematoxylin and eosin–stained pathology images in lung adenocarcinoma.
2019年5月7日 · This tool can computationally “stain” different types of cell nuclei in H&E pathology images to facilitate pathologists in analyzing the TME. A Mask Regional-Convolutional Neural Network (MaskRCNN) model - was developed to segment
Computational Staining of Pathology Images to Study the Tumor ... - PubMed
2020年5月15日 · To facilitate the study of cellular spatial organization and interactions, we developed Histology-based Digital-Staining, a deep learning-based computation model, to segment the nuclei of tumor, stroma, lymphocyte, macrophage, karyorrhexis, and red blood cells from standard hematoxylin and eosin-stained pathology images in lung adenocarcinoma.
Immuno-profiling and cellular spatial analysis using five immune ...
2021年4月19日 · These optimized mIF staining panels can be used to study the inflammatory tumor repertoire, immune checkpoints, and myeloid suppressor markers that have several implications for translational...
NIR‐II image‐guided surgically resected multiple‐microtumor. (a)...
(g) H&E and immunofluorescence staining of the resected tumors, in which green means VEGF, blue means cell nucleus (DAPI), and white dotted line means normal tissue. The red dotted line of the H&E ...
Stain normalization methods for histopathology image analysis: A ...
2024年2月1日 · In this context, an effective stain normalization method has proved as a powerful tool to standardize different color appearances and minimize color variations in histopathology images. This study reviews different stain normalization methods highlighting the main methodologies, contributions, advantages, and limitations of correlated works.
Multiplex three-dimensional optical mapping of tumor …
2017年12月5日 · Cutting tumors into sub-millimeter macrosections enables simple and rapid immunofluorescence staining, optical clearing, and confocal microscope imaging. Registering and fusing macrosection...
Addressing persistent challenges in digital image analysis of …
2023年7月21日 · Here we discuss methods for feature extraction using variational autoencoders (VAEs), automated summarizing of high dimensional data with thumbnail images, and predicting marker staining intensities from H&E images.