Acetoacetic acid - Wikipedia
Under typical physiological conditions, acetoacetic acid exists as its conjugate base, acetoacetate: AcCH 2 CO 2 H → AcCH 2 CO − 2 + H + Unbound acetoacetate is primarily produced by liver mitochondria from its thioester with coenzyme A (CoA): AcCH 2 C(O)−CoA + OH − → AcCH 2 CO − 2 + H−CoA. The acetoacetate-CoA itself is formed by ...
Acetoacetate | C4H5O3- | CID 6971017 - PubChem
Acetoacetate | C4H5O3- | CID 6971017 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Acetoacetate: What is it, Why It's Important & The Benefits
2022年9月24日 · Acetoacetate is the first ketone body produced in the liver while keto dieting. It’s the precursor to beta-hydroxybutyrate (BHB), a vital energy source when you’re in ketosis. What is the function of acetoacetate?
What Is Acetoacetate? What You Need to Know - Perfect Keto
2024年10月23日 · Acetoacetate is the first ketone produced in the body during ketosis. It’s important because it’s the precursor to beta-hydroxybutyrate, which is a vital energy carrier when you’re in ketosis. Acetoacetate is completely safe, but it is commonly confused with ethyl acetoacetate, which has various health warnings.
酮体代谢及酮体的多种生理功能 - 知乎 - 知乎专栏
脂解产生的乙酰辅酶A除了进入三羧酸循环氧化之外，还可以在肝脏中合成酮体（ketone body）。酮体指乙酰乙酸、β-羟基丁酸和丙酮这三种物质。 酮体主要是在缺乏葡萄糖时作为肝外组织的能源物质。心脏和肾上腺皮质主…
Ethyl acetoacetate - Wikipedia
The organic compound ethyl acetoacetate (EAA) is the ethyl ester of acetoacetic acid. It is a colorless liquid. It is widely used as a chemical intermediate in the production of a wide variety of compounds.
Ketone bodies - Wikipedia
When two acetyl-CoA molecules lose their -CoAs (or coenzyme A groups), they can form a (covalent) dimer called acetoacetate. β-hydroxybutyrate is a reduced form of acetoacetate, in which the ketone group is converted into an alcohol (or hydroxyl) group (see illustration on the right). Both are 4-carbon molecules that can readily be converted ...
Acetoacetate - an overview | ScienceDirect Topics
Acetoacetate is a compound used in a chemical system to determine trichothecene mycotoxins like deoxynivalenol (DON) and nivalenol (NIV) in food samples. It reacts with formaldehyde and ammonium to form fluorescent dihydropyridine derivatives in a two-step modified Hantzsch synthesis process.
Acetoacetate protects macrophages from lactic acidosis …
2021年12月8日 · Meanwhile, acetoacetate, a natural metabolite produced by the liver, is utilized by monocytes/macrophages as an alternative fuel to mitigate lactic acidosis-induced pseudostarvation, as evidenced...
Acetoacetic acid | C4H6O3 | CID 96 - PubChem
It is a conjugate acid of an acetoacetate. It is a tautomer of a 3-hydroxy-3-butenoic acid.