BALB/c - Wikipedia
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation .
000651 - BALBc Strain Details - The Jackson Laboratory
000651 BALB/cJ BALB/cJ is a commonly used inbred. Key traits include a susceptibility to developing the demyelinating disease upon infection with Theiler's murine encephalomyelitis virus. The BALB/cJ substrain is susceptible to Listeria , all species of Leishmania , and several species of Trypanosoma , but is resistant to experimental allergic orchitis (EAO).
BALB/c - an overview | ScienceDirect Topics
BALB/c Mouse. H. Nakamura, in Brenner's Encyclopedia of Genetics (Second Edition), 2013 Characteristics. The BALB/c mice are, in general, light-sensitive and possess susceptibility to stress-responsive and anxious tendency. Most substrains of BALB/c have a long reproductive life span, resulting in good breeding performance, and are relatively resistant to diet-induced …
C57BL/6 and BALB/c Mouse Models | Cyagen
2020年3月30日 · BALB/c mice tend to produce a stronger humoral response than C57BL/6 mice. These strains have different gene sequences at the H2 site of the major histocompatibility (MHC)class I gene locus - BALB/c mice is H2d, while C57BL/6 is H2b. The difference in gene sequence of these two strains falls on the H2 locus.
The BALB/c Mouse: Genetics and Immunology | SpringerLink
Today the BALB/c mouse is among the five most widely used inbred strains in biomedical research and a particular favorite in immunology and infectious disease research. The hallmark of the BALB/c response to so many kinds of infections is susceptibility and sometimes an exaggerated susceptibility, but this paradoxically is not associated with ...
BALB/c Mice | Charles River
BALB/c mice is also known for being relatively resistant to diet-induced atherosclerosis, making them ideal for cardiovascular research. BALB/c 3T3 cell lines are highly disposed to transformation in tissue culture by the oncogenic DNA virus SV40 and murine sarcoma virus, making them a model of choice for carcinogenesis research. ...
BALB/cJ and BALB/cByJ: How can I choose? I’m so confused!
A substrain can arise in a couple of ways: 1) when a spontaneous mutation becomes fixed in a colony, and that colony is maintained as a separate line, 2) when mice from the same parent colony are maintained separately for 20 generations or more. Let’s focus on the second way. Suppose you and I obtained BALB/c mice from the same source.
MGI - Inbred Strains: BALB - The Jackson Laboratory
Following administration of murine cytomegalovirus, BALB/c, BALB.B, and BALB.K mice develop persistent myocarditis regardless of age at infection, and age-related cardiopathy is frequent and severe in infected and uninfected mice (contrast C57BL/10 and C3H) (Price et al 1991).
BALB/c inbred mice - Inotiv
2024年4月20日 · BALB/c mice have proven to be a reliable model in neuroscience research, facilitating the study of neurodegenerative diseases such as Alzheimer's and Parkinson's. This mouse model has served as a proven background strain for the development of novel transgenic mouse strains, thereby providing valuable insights into disease pathology and the ...
The BALB/c mouse: Effect of standard vivarium lighting on …
1. Introduction. The BALB/c mouse has been used in the laboratory for over a century (JAX® Notes Issue 443, 1990).Initially referred to as “Bagg” mice, this strain became an inbred line in the early 1920's and is now one of the most popular breeds of laboratory mice used in medical research (Mouse Genome Informatics Web Site, 2013).This line is available from multiple …
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