Extracellular Space - an overview | ScienceDirect Topics
The extracellular space of any multicellular organism contains many different components, such as ions, proteins, oligosaccharides and metabolites, which are released from all cell types.
Brain Extracellular Space: Geometry, Matrix and Physiological ...
Extracellular space is the immediate external environment of brain cells. This proximity to the cell membrane makes the structure and content of the ECS important for cellular homeostasis and function.
Extracellular Space - an overview | ScienceDirect Topics
The extracellular space (ECS) is the microenvironment of the nerve cells and an important communication channel, allowing for long-distance extrasynaptic ‘volume’ communication by the diffusion of neuroactive substances between cells.
Brain Extracellular Space: The Final Frontier of Neuroscience
2017年11月21日 · Brain extracellular space is the narrow microenvironment that surrounds every cell of the central nervous system. It contains a solution that closely resembles cerebrospinal fluid with the addition of extracellular matrix molecules.
Current Techniques for Investigating the Brain Extracellular Space
2020年10月14日 · The brain extracellular space (ECS) is a continuous reticular compartment that lies between the cells of the brain. It is vast in extent relative to its resident cells, yet, at the same time the nano- to micrometer dimensions of its channels and reservoirs are commonly finer than the smallest cellular structures.
Unveiling the Extracellular Space of the Brain: From Super …
2018年10月31日 · The extracellular space occupies approximately one-fifth of brain volume, molding a spider web of gaps filled with interstitial fluid and extracellular matrix where neurons and glial cells perform in concert.
Brain Extracellular Space: The Final Frontier of Neuroscience
2017年11月21日 · Brain extracellular space is the narrow microenvironment that surrounds every cell of the central nervous system. It contains a solution that closely resembles cerebrospinal fluid with the addition of extracellular matrix molecules.
The Extracellular Matrix of Animals - Molecular Biology of the …
A substantial part of their volume is extracellular space, which is largely filled by an intricate network of macromolecules constituting the extracellular matrix (Figure 19-33). This matrix is composed of a variety of proteins and polysaccharides that are secreted locally and assembled into an organized meshwork in close association with the ...
Advancement in modulation of brain extracellular space and …
2024年5月3日 · Cells in the brain are surrounded by extracellular space (ECS), which forms porous nets and interconnected routes for molecule transportation. Our view of brain ECS has changed from a largely static compartment to dynamic and diverse structures that actively regulate neural activity and brain states.
Super-Resolution Imaging of the Extracellular Space in Living …
2018年2月22日 · Live tissue super-resolution 3D-STED microscopy combined with fluorescence labeling of the interstitial fluid reveals the complex spatial organization of the extracellular space of the brain.
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