Histidine - Wikipedia
Histidine, along with other amino acids such as proline and arginine, takes part in deamination, a process in which its amino group is removed. In prokaryotes, histidine is first converted to …
Protonation, Tautomerization, and Rotameric Structure of Histidine…
2011年1月5日 · Histidine protonation states are key in the LigI catalytic reaction mechanism. Proteins: Structure, Function, and Bioinformatics 2022 , 90 (1) , 123-130. …
Can the protonation state of histidine residues be determined …
2012年11月15日 · Histidine (His) residues in proteins can attain three different protonation states at normal pH. This constitutes a prominent problem when adding protons to a protein crystal …
Histidine in Proteins: pH-Dependent Interplay between π–π, …
2024年7月22日 · Histidine (His) stands out as the most versatile natural amino acid due to its side chain’s facile propensity to protonate at physiological pH, leading to a transition from aromatic …
Frontiers | Determination of Histidine Protonation States in …
2021年12月9日 · Protonation states for the crystalline histidine amino acid have been determined by MAS NMR for different pH values (Li and Hong, 2011) and crystalline short peptides …
Histidine in Proteins: pH-Dependent Interplay between π–π, …
Histidine (His) stands out as the most versatile natural amino acid due to its side chain’s facile propensity to protonate at physiological pH, leading to a transition from aromatic to cationic …
Effects of histidine protonation and rotameric states on virtual ...
In this study, we focus on histidine protonation and rotameric states and their impact on virtual screening of Mycobacterium tuberculosis enzyme RmlC. Depending on the net charge and the …
Protonation and geometry of histidine rings - PMC - PubMed …
Protonation states and B-factor ranges of atoms in the imidazole moieties of the histidine residues in PDB structure 4rj2. If an N atom is protonated and serves as a hydrogen-bond donor it is …
Determination of Histidine Protonation States in Proteins by
2021年12月10日 · Histidine residues play important structural and functional roles in proteins, such as serving as metal-binding ligands, mediating enzyme catalysis, and modulating proton …
Protonation State of an Important Histidine from High …
2022年1月24日 · EH99 automatically assigns a double protonation state to histidine, whereby both the nitrogen atoms, Nδ1 and Nε2 have a covalently linked hydrogen atom.