IFN-γ selectively suppresses a subset of TLR4-activated genes and ...
2019年7月25日 · ChIP-qPCR showed that IFN-γ blocked LPS-induced recruitment of STAT3 and the AP-1 protein c-Jun to e4 enhancers at the IL10 locus (Fig. 3g, h). Overall, these data …
Lipopolysaccharide-Induced Vascular Inflammation Model on Microfluidic Chip
2020年7月31日 · In this paper, we focused on the inflammatory response of blood vessels on microfluidic chips infiltrated by LPS from the basal side of blood vessels to mimic a situation …
Human GBP1 binds LPS to initiate assembly of a caspase-4 ... - Nature
2020年6月24日 · Detection of lipopolysaccharide (LPS) is central to host defense against Gram-negative bacterial infections and to the pathogenesis of sepsis. Extracellular LPS is sensed...
Negative elongation factor complex enables macrophage …
2020年5月8日 · We used findPeaks program in HOMER to call NELF-E ChIP-seq peaks, with LPS 0.5 h condition as background and LPS 0 h condition as enrichment, to identify genes …
Transcriptional profiling of the LPS induced NF-κB response in ...
2007年1月12日 · Exposure of macrophages to bacterial products such as lipopolysaccharide (LPS) results in activation of the NF-κB transcription factor, which orchestrates a gene …
Analysis of lipopolysaccharide (LPS)-binding characteristics of …
2000年8月28日 · The interaction of isolated HDL (1 to 100 μg/ml), rsCD14 (10 to 200 μg/ml), rLBP (10 to 100 μg/ml) and albumin (100 to 2000 μg/ml) with LPS was studied with the BIACORE X …
RNA-Binding Proteins in the Control of LPS-Induced Macrophage …
2019年2月4日 · We discuss recent experiments employing RNA immunoprecipitation and microarray analysis (RIP-Chip) and newly developed individual-nucleotide resolution …
Lipopolysaccharide-dependent transcriptional regulation of …
2019年12月5日 · Stimulation with lipopolysaccharide (LPS) or interferon-gamma (IFNγ) induces the classically activated (M1; pro-inflammatory) state relevant for defense against bacterial …
Delineation of Lipopolysaccharide (LPS)-binding Sites on …
2011年10月10日 · Background: Redox activity of hemoglobin (Hb) is augmented by lipopolysaccharide (LPS) to boost immune defense. Results: Computational analysis of Hb …
Affinities of Different Proteins and Peptides for Lipopolysaccharide …
1998年11月18日 · Biosensor technology was employed to study the specific interactions of different lipopolysaccharide (LPS)-binding proteins and peptides with LPS, using an LPS …