Metalation - Wikipedia
Metalation (Alt. spelling: Metallation) is a chemical reaction that forms a bond to a metal. This reaction usually refers to the replacement of a halogen atom in an organic molecule with a metal atom, resulting in an organometallic compound.
Metalation | Catalytic, Reductive & Oxidative | Britannica
metalation, any chemical process by which a metal atom is introduced into an organic molecule to form an organometallic compound, but more commonly the process involving a hydrogen–metal exchange. An example is the metalation of benzene (C 6 H 6) by reaction with ethylsodium (C 2 H 5 Na), forming phenylsodium (C 6 H 5 Na) and ethane (C 2 H 6).
The direct metalation group (DMG) is typically a Lewis basic moiety that interacts with the Lewis acidic lithium cation allowing for deprotonation by the alkyl-lithium species from the nearest ortho-position on the arene.
Protein metalation in biology - PMC - National Center for ...
This article focuses on the process of metalation, the acquisition of metals by proteins, within living organisms. More specifically, it addresses the fidelity of the metalation process that enables the elements with the required chemical properties to become bound to each individual protein.
Protein metalation in biology - PMC
This article focuses on the process of metalation, the acquisition of metals by proteins, within living organisms. More specifically, it addresses the fidelity of the metalation process that enables the elements with the required chemical properties to become bound to each individual protein.
Protein metalation in a nutshell - PMC - National Center for ...
2022年9月26日 · Metalation of proteins is logical within defined intracellular metal availabilities. Mis‐metalation is avoided because weaker binding metals are more available than tighter binding ones. Metalation is crucial for metalloproteins to achieve …
Metalation - an overview | ScienceDirect Topics
Metalation in chemistry refers to the substitution of hydrogen atoms in a molecule with metal atoms, typically achieved by depositing metal atoms onto a substrate or by evaporating metal atoms onto a molecular layer.