Monocarboxylate transporter - Wikipedia
The monocarboxylate transporters, [1] or MCTs, are a family of proton-linked plasma membrane transporters that carry molecules having one carboxylate group (monocarboxylates), such as …
Monocarboxylate Transporter - an overview | ScienceDirect Topics
Monocarboxylate transporters (MCTs) are proteins that play a crucial role in various metabolic pathways by facilitating the transport of L-lactate and pyruvate across the cell membrane. …
Monocarboxylate Transporters (SLC16): Function, Regulation, …
MCTs 1, 2, and 4 (L-lactate transporters) are overexpressed in cancers and represent a novel therapeutic target in cancer. Recent studies have highlighted the importance of MCTs in …
Cell：闫创业/蒋鑫团队合作揭示单羧酸转运蛋白的质子偶联转运机 …
2020年12月16日，清华大学研究员闫创业课题组和澳大利亚新南威尔士大学研究员蒋鑫课题组合作在Cell上发表了文章 Structural basis of human monocarboxylate transporter 1 inhibition by …
单羧酸转运蛋白家族介导乳酸转运在肿瘤发生发展中的作用
单羧酸转运蛋白（monocarboxylate transporters，MCTs）为溶质运载蛋白16（solute carrier 16，SLC16）家族的一部分。 MCTs的主要功能是介导质子耦连的乳酸等单羧酸类物质的跨膜 …
The monocarboxylate transporter family--Structure and …
Monocarboxylate transporters (MCTs) catalyze the proton-linked transport of monocarboxylates such as L-lactate, pyruvate, and the ketone bodies across the plasma membrane. There are …
Monocarboxylate Transporters: Therapeutic Targets and …
In particular, the SLC16 family that encodes for the 14 isoforms of the monocarboxylate transporter (MCT) family plays a significant role in the absorption, tissue distribution, and …
Monocarboxylate Transporter - an overview | ScienceDirect Topics
Monocarboxylate transporters (MCTs) are proteins belonging to the family of plasma membrane transporters SLC16A, with 14 members identified so far. MCTs are transmembrane proteins, …
Monocarboxylate Transporter - an overview | ScienceDirect Topics
Monocarboxylate transporters (MCTs) comprise a family of proton-linked plasma membrane transporters that move monocarboxylates across cell membranes. 10 These transporter …
Monocarboxylate transporters in the brain and in cancer - PMC
Monocarboxylate transporters (MCTs) constitute a family of 14 members among which MCT1–4 facilitate the passive transport of monocarboxylates such as lactate, pyruvate and ketone …