Natural killer cell therapies - Nature
2024年2月21日 · Natural killer (NK) cells are lymphocytes of the innate immune system. A key feature of NK cells is their ability to recognize a wide range of cells in distress, particularly …
NK Cell Therapy: A Rising Star in Cancer Treatment - PMC
Compared with other immunotherapies, NK cell therapy has its advantages. With their major histocompatibility complex (MHC)-antigen stimulating independent cytotoxicity, better safety, …
What is CAR NK therapy? | MD Anderson Cancer Center
2024年5月15日 · CAR NK cell therapy bolsters the body’s innate ability to fight cancer by attaching molecules called chimeric antigen receptors (CAR) to natural killer cells (NK cells). …
NK Cell Therapy: A Rising Star in Cancer Treatment - PubMed
2021年8月17日 · This review describes the current status of NK cell therapy for cancer treatment based on the effector function and releasing the inhibited state of NK cells in the cancer …
NK cell-based cancer immunotherapy: from basic biology to …
2021年1月6日 · In this review, we provide our current understandings of NK cell biology, ongoing pre-clinical and clinical development of NK cell-based therapies and discuss the progress, …
Natural killer cells in antitumour adoptive cell immunotherapy
2022年7月25日 · Strategies for the development of NK cell-based therapies focus on enhancing NK cell potency and persistence through co-stimulatory signalling, checkpoint inhibition and …
Advances in NK cell therapy for brain tumors - Nature
2023年2月15日 · In this review, we explore the mechanisms by which the brain tumor microenvironment suppresses NK cell mediated tumor control, and the methods being used to …
Natural killer cells: a promising immunotherapy for cancer
2022年5月23日 · As a promising alternative platform for cellular immunotherapy, natural killer cells (NK) have recently gained attention as an important type of innate immune regulatory …
Natural killer cells: the next wave in cancer immunotherapy
We will discuss the prognostic roles of NK cells in cancers, summarize the contributions of NK cells in the success of immune checkpoint blockade (ICB) therapies and approaches including …
Emerging NK cell therapies for cancer and the promise of next ...
Here, we review multiple avenues for allogeneic NK cell therapy, including derivation of NK cells from peripheral blood or umbilical cord blood, the NK-92 immortalized cell line, and induced …