Permethrin: Uses, Interactions, Mechanism of Action - DrugBank …
Permethrin, a pyrethroid, is active against a broad range of pests including lice, ticks, fleas, mites, and other arthropods. Permethrin acts on the nerve cell membrane to disrupt the sodium channel current by which the polarization of the membrane is regulated.
Permethrin - StatPearls - NCBI Bookshelf
2024年2月29日 · Permethrin, a synthetic pyrethroid categorized as a synthetic neurotoxic pyrethroid, is approved for treating scabies and pediculosis capitis. This medication operates within the arthropod nervous system, specifically targeting eggs, lice, and mites.
Permethrin - Wikipedia
Permethrin is a medication and an insecticide. [4][5] As a medication, it is used to treat scabies and lice. [6] . It is applied to the skin as a cream or lotion. [4] . As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them. [5][7]
Permethrin: Dosage, Mechanism/Onset of Action, Half-Life
2020年2月10日 · Includes Permethrin indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more.
Permethrin - PubMed
2024年2月29日 · Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis.
Permethrin: uses, dosing, warnings, adverse events, interactions
Permethrin 1% generally is considered the treatment of choice and malathion 0.5% is recommended when permethrin resistance is suspected.
Permethrin - an overview | ScienceDirect Topics
Permethrin is a synthetic pyrethroid, formed by the modification of the molecular structure of pyrethum, the flower heads of chrysanthemum cinerariaefolium. It is also used in veterinary practice, animal husbandry, and agriculture for the control of arthropod pests and ectoparasites.
Resistance and Pseudo-resistance to permethrin: the importance …
Permethrin acts on the nerve cell membrane by disrupting the function of voltage-gated sodium channels (VGSCs). This results in delayed repolarization and subsequent paralysis and death of the parasite in all stages ( Lobo and Wheller, 2021 ).
Permethrin, a pyrethroid insecticide, regulates ERK1/2 activation ...
Permethrin is the most widely used pyrethroid and acts as an agonist on neuronal voltage-sensitive sodium channels (VSSC) where it causes membrane depolarization, resulting in death of insects (Vais et al., 2001).
Permethrin Pharmacology - Active Ingredient - RxReasoner
Chemical formula: C₂₁H₂₀Cl₂O₃ Molecular mass: 391.288 g/mol PubChem compound: 40326. Permethrin belongs to a group of medicines called pyrethroids which are anti-parasitic agents. Permethrin is rapidly absorbed across the insect cuticle.